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If you were to use one 2.4 mg pen across the full 12-week titration schedule (0.25 for 4 weeks, increasing to 0.5 for 4 weeks, then 1.0 mg for 4 weeks) and ignore the medication expiry window, heres how it would break down: That leftover 2.6 mg could then provide: Total duration from one pen: up to 13 weeks (if ignoring expiry guidance)

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Instruct patients to inform healthcare providers prior to any planned surgeries or procedures if they are taking RYBELSUS [see Warnings and Precautions (5.9)]