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In recent enforcement actions, the agency identified multiple concerns with compounded GLP-1 products: use of incorrect salt forms of semaglutide that have not been studied for safety, dosing errors due to patient-drawn injections from multi-dose vials, improper storage and shipping conditions, and misleading marketing that implies FDA equivalence

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Hormonal or thyroid changes

continue this schedule without interruption when adding semaglutide

The balance of benefits and risks associated with weight-loss drugs may be less favorable for older people than the younger ones, making it necessary to study further how these drugs work for people aged 65 and older, they write