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And I think hope comes in the form of having viable treatments

The GLP-1 receptor agonist exenatide ameliorates neuroinflammation, locomotor activity, and anxiety-like behavior in mice with diet-induced obesity through the modulation of microglial M2 polarization and downregulation of SR-A4

This finding was significant enough that the tirzepatide drug label now advises patients using oral hormonal contraceptives to switch to or add a non-oral contraceptive method when initiating tirzepatide and after each dose escalation

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Some unanswered questions remain, though, about how these drugs would affect addiction