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According to NICE guideline NG193 (Chronic pain in over 16s), diagnosis is clinical and based on widespread pain lasting more than three months, along with associated symptoms

Step 4: Continue on the new day going forward

Patients who maintain a structured meal plan and add 150 minutes of weekly activity see belly fat improvements 23 weeks faster than those relying on medication alone

Cardiometabolic Improvements Weight loss was accompanied by clinically meaningful improvements across several cardiovascular risk markers, including reductions in: Waist circumference (mean reduction of approximately 24.1 cm at the highest dose) Non-HDL cholesterol Triglycerides Systolic blood pressure High-sensitivity C-reactive protein (hsCRP) a marker of inflammation These findings are particularly relevant for patients with obesity who also live with cardiometabolic conditions, where systemic risk reduction is as important as the weight loss itself