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Recent reports raise very serious concerns that delayed gastric emptying from GLP-1 agonists increases the risk of regurgitation and aspiration during general anesthesia and deep sedation care
In the pancreas, glucagon has physiologically relevant cross-reactivity with GLP-1R, with an EC 50 of 36.4 0.22 nM, but there is no affinity of GLP-1 to the glucagon receptor [365]
Adv Exp Med Biol 2021;1307:171-192
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On the contrary, for the same treatment period but at a drug concentration of 1.0 mg, there was only 1 case of thyroid cancer (Table 4)
