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For patients with type 2 diabetes or prediabetes, this dual benefit of weight loss and glycemic control is particularly advantageous

Gastrointestinal side effects, including nausea, vomiting, diarrhea, and abdominal discomfort, are commonly reported, particularly during the initial weeks of treatment or following dose escalation

Individual timelines vary based on diet, dose, and personal microbiome composition, but this side effect is almost always temporary

While not yet FDA approved, trials have pointed to Retatrutide side effects similar to those seen in existing GLP-1 medications

They function by targeting insulin resistance, a common underlying issue in many weight-related health problems