Dosing Schedule
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Description
The added upregulation of GIP in dual-acting and triple-acting agonists, such as tirzepatide and retatrutide, respectively, resulted in greater reductions in weight loss and insulin sensitivity when compared to medications that acted at the GLP-1 receptor alone
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they also have robust benefits on reducing the incidence of macroalbuminuria.
It highlights common gastrointestinal effects, rare but debated risks, and areas where further long-term safety data are still needed.
Its a peptide
