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Pearce, MD, MSc, Professor of Medicine at Boston University, spoke about the challenges in investigating causal associations between incretin therapies and a rare solid tumor, like thyroid cancer

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This was evidenced by increased alkaline phosphatase (ALP) activity, enhanced mineralization, and upregulation of osteogenic markers such as osteocalcin (OCN) and Runt-related transcription factor 2 (RUNX2)