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Since then, a number of studies have also been conducted in human primary hepatocytes, providing evidence for the direct effect of GLP-1 binding with GLP-1R in hepatocytes on reducing liver lipids [64]

Traditional treatments often fail to address these multidimensional processes, highlighting the need for novel therapeutic strategies

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Tirzepatide (Zepbound, Mounjaro) : discontinue at least 1 month before pregnancy per Canadian labeling
