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Mechanisms, pathophysiology, and management of obesity

Association between weight loss, change in physical activity, and change in quality of life following a corporately sponsored, online weight loss program

Real-world data published in JAMA confirmed that tirzepatide was associated with significantly greater weight loss than semaglutide in clinical practice, not just in controlled trial settings

In cases, the drugs may cause ileus, a digestive problem leading to bowel movement difficulties

Patients and their doctors may not have been able to make a fully informed decision, weighing the benefits of the drug against its potential for causing a life-altering gastrointestinal injury