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Moreover, for people already dealing with substance abuse, it decreased adverse events and the risk of death by 50%.[ref] Which GLP-1 Agonists are Approved for Weight Loss

The funder of this study had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

The presence of obesity-related complications such as obstructive sleep apnea, metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD), or cardiovascular disease may justify longer treatment duration given the health benefits of sustained weight loss

Duric et al., 2013)

Activation of GLP-1R in the PVN stimulates the release of oxytocin, which exerts anorexigenic effects [13]