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Spironolactone is generally considered a safe diuretic that doesnt cause potassium loss

2025;101(5):1068-1072.e1
Without comprehensive lifestyle support, these medications may offer only temporary weight lossa reality that underscores why structured nutrition, behavioral support, and medical monitoring are not optional add-ons but essential components of any GLP-1 treatment plan

in two cases oral semaglutide was prescribed in addition to SGLT2-I, and in two cases subcutaneous semaglutide was added to basal insulin

Oral and sublingual formulations have different bioavailability profiles that can affect both the timeline and magnitude of results
