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Description

GLP-1 receptor agonists (GLP-1RAs) are well established for glycemic control and weight reduction in patients with type 2 diabetes mellitus (T2DM) and/or obesity and have demonstrated cardiovascular benefit [2]

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GLP-1RAs and SGLT2 inhibitors also have pleiotropic effects, including blood glucose-dependent and -independent mechanisms, effects on the reninangiotensinaldosterone system and favourable effects on left ventricular and renal functions [35, 36]

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