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Step therapy can be waived with documented intolerance to phentermine, prior failure to lose weight on phentermine, or contraindication (cardiovascular disease, uncontrolled hypertension, seizure history)

The gut microbiota in the cecum and feces are similar, but not necessarily the same

While weight-loss medications offer significant benefits for many patients, experts say maintaining body weight and muscle mass remains an important consideration for people with neurodegenerative diseases

2022 JAMA Internal Medicine meta-analysis: pooling 76 randomised controlled trials, GLP-1 receptor agonist use was associated with a relative risk of 1.37 for biliary disease compared with placebo or other treatments

Stay Hydrated Drink at least half your body weight in ounces of water daily (e.g., 180 lbs = 90 oz water) to support digestion, energy, and appetite control