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It is now available online as a research letter in Diabetes, Obesity & Metabolism.

This enzyme helps regulate how cells use and store energy, promoting more efficient fat and carbohydrate metabolism and supporting balanced blood sugar levels

A collaborative study carried out by the team "Functional Pharmacology and Physiopathology of Membrane Receptors" led by Dr Ralf Jockers, and published in Nature Metab., shows that mutations of the gene encoding the receptor of glucagon-like peptide 1 (GLP1R) affect metabolic traits such as glucose and body weight management and modulates the effectiveness of GLP1R agonists clinically used to treat diabetic and/or obese patients.

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