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Doctor Evaluation Complete a detailed intake form for review by a board-certified doctor, who will recommend a personalized, medication-assisted treatment plan

This side effect appears to be driven by multiple factors, including Mounjaros impact on the brain, reduced peripheral blood flow, decreased thermogenesis from lower food intake, and reduced insulation from weight loss

Fuentes N, Silveyra P

57 UPR is mainly involved in the activation of three transmembrane proteins, inositol-requiring enzyme 1 (IRE-1), activating transcription factor 6 (ATF6), and protein kinase R (PKR)-like ER kinase (PERK)

Diet and exercise are the expected initial approach to treat these patients, with GLP-1R agonists prescribed as second-line drugs for patients who are refractory to the current standard of care