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Description
Landmark preclinical studies using animal knockouts have demonstrated that GLP-1 receptors in the brain are capable of controlling food intake and body weight, in addition to the hypophagic effects of endogenous GLP1 via peripheral GLP1 receptors [33]
Notably, these perturbations were significantly mitigated by dulaglutide therapy

Interestingly, mog-3 partially mimics male/mating-induced demise, offering a simplified model to study metabolic and reproductive trade-offs underlying this phenomenon
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Author: Pharmko, Inc
