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Genetic deletion of GSK3 in mice results in behaviours that mimic the mood-stabilising effects of lithium, as well as causing cognitive deficits similar to those associated with chronic lithium treatment in humans [166,167,168,169]

Contact your GP if you experience these symptoms, as neurological damage from B12 deficiency can become irreversible if left untreated

North America leads due to strong R&D capacity, presence of major pharmaceutical players, and supportive regulatory frameworks

Any weight lost during treatment will return if treatment stops

In contrast, GLP-1RAs provide prolonged systemic effects, making them well-suited for managing chronic conditions like T2D and obesity