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The enrollment period lasted from August 30, 2019, to March 20, 2020, and follow-up was completed on January 13, 2021.The participants were divided into four groups in a 1:1:1:1 ratio
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For chronic weight management, tirzepatide works by engaging multiple hormonal pathways, including the GIP and GLP-1 receptors, which are crucial for metabolic regulation, blood sugar control, appetite management, and energy expenditure

Andrew Kraftson, MD, the director of the weight navigation program at Michigan Medicine in Ann Arbor, believes strongly in the value of medications like semaglutide and understands why people are scrambling to get them

Am J Physiol Endocrinol Metab
