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Between 30 million and 50 million US adults could be taking a GLP-1 by 2034. In December 2024, 1.9 million prescriptions of GLP-1s to treat obesity (as opposed to diabetes, for example) were filled, nearly quadruple the number YoY, per IQVIA

Outcomes included changes in left ventricular ejection fraction (LVEF), end-diastolic volume (LVEDV), end-systolic volume (LVESV), global longitudinal strain (GLS), left ventricular mass, left atrial volume (LAV), and NT-proBNP levels

An effective treatment might require either utilization of multiple drugs which target the individual pathological processes which underlie the neurodegenerative disease or the use of a single agent which could influence multiple pathological processes