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Description
Evolus has since submitted the final module of its Premarket Approval application to the FDA

This mechanism complements Retatrutides appetite suppression and metabolic rate enhancement with targeted visceral fat reduction

It acts as a highly selective agonist at receptors of the incretins GLP-1 and GIP, thereby increasing the amount of insulin released in a glucose-dependent manner

Drinking plenty of water throughout the day is also key to staying hydrated and supporting digestion

Notably, despite the positive effects on renal outcomes, the study also reported an increased incidence of gastrointestinal side effects, including nausea, vomiting, and diarrhea, though these were not statistically significant [89]
