semaglutide brain VT750 distribution in mouse brain. (A) Acute and (B) The Unexplored Effects of Weight-Loss

GLP-1 Medications and Mental Health: What Weve Learned Since 2023 December 26, 2025 | Updated from our original September 2023 post In September 2023, I wrote about semaglutide (commonly known by brand names such as Wegovy and Ozempic) in response to a growing number of client questions

Choosing between GLP-1 and GLP-2 (GLP-3 is not a current option) depends entirely on your health goals and conditions: Choose GLP-1 If Youre Focused On: Blood sugar control and diabetes management Weight loss and appetite suppression Metabolic health optimization Cardiovascular risk reduction Overall metabolic syndrome improvement Choose GLP-2 If Youre Dealing With: Short bowel syndrome Inflammatory bowel disease Malabsorption issues Intestinal damage or injury Chronic gut inflammation Need for improved nutrient absorption Consider Medical Consultation Neither GLP-1 nor GLP-2 should be started without proper medical evaluation

Mounjaro is currently recommended by NICE as a weight loss medication, even for individuals without type 2 diabetes

J Reprod Infertil

How the Gallbladder Functions During Rapid Weight Loss The gallbladder stores bile between meals and releases it during digestion, helping your body break down dietary fats