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obesity, eating disorders, diabetes, drug addiction and nausea / malaise)

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Adequate tryptophan intake supports de novo synthesis, though inflammatory diversion toward kynurenine metabolites limits this pathway under conditions of immune activation

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In this study, the animals received the GLP-1A exenatide (0.5 1 g.kg 1 BID) for 12 weeks, but the treatment did not resulted in differences in total weight, percentage of body fat, glycemia, leptin, adiponectin, glucagon and in glucose and insulin tolerance tests (GTT and ITT) (Hoelmkjaer et al., 2016)