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In vitro, the protein levels of IL-1 and TNF- in lipopolysaccharide-stimulated BV-2 microglia were also decreased by liraglutide

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Pre-treatment with a GLP1 receptor-blocking antibody neutralised the CNO-dependent improvement in glucose tolerance but did not affect the reduction in food intake, and an independent group of animals pair-fed to the CNO-treatment group demonstrated attenuated weight loss

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