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B12 deficiency becomes more common on GLP-1 therapy, so some patients benefit from monthly B12 injections or sublingual supplements in addition to a standard multivitamin

The actual skeletal muscle loss is comparable to what occurs with any form of calorie restriction

Stretching doses to every two weeks creates a rollercoaster effect: high drug exposure in days one through three, followed by a prolonged period of declining therapeutic benefit

For example, ATG = Methionine, TTC = Phenylalanine, CCA = Proline