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Description
Allard MF, Schnekess BO, Henning SL, English DR, Lopaschuk GD

Pflgers Archiv

We identify mitochondrial trifunctional protein- (MTP) as a binding partner of GLP-1(2836) and demonstrate that the ability of GLP-1(2836) to shift substrate utilization from oxygen-consuming fatty acid metabolism toward oxygen-sparing glycolysis and glucose oxidation and to increase cAMP levels is dependent on MTP
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RodriguezPZhangVGratzlSDoDGoodwin CartwrightBBakerCet al

In clinical studies, participants taking semaglutide GLP-1 lost more weight on average than those taking liraglutide or other GLP-1 medications
