glp 1 new indications Blog | Discover Your Weight Journey—Get Informed — Navigate Weight & Metabolic How underwriters should interpret GLP-1
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In this complex scenario, the concomitant presence of obesity further increases insulin resistance and exacerbates the clinical presentation of PCOS

Further prospective trials with shot-gun sequencing should be done
[52] Clinical trials shown that GLP-1 receptor agonists improve menstrual regularity , decrease body weight and central adiposity, increase sex hormone-binding globulin levels , and lower free testosterone in overweight and obese women with PCOS

GLP-1 has opposing effects on hepatic lipid accumulation and plasma lipid levels, which has recently broadened its clinical use in pharmacological therapy of metabolic syndrome and steatohepatitis 8,9
