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GLP-1 receptor agonists also reduce the three components of MACE, including CV mortality (reduced by 13%), nonfatal stroke (reduced by 16%) and nonfatal myocardial infarction (reduced by 9%, although the level of significance was not reached)

Do gut hormones contribute to weight loss and glycaemic outcomes after bariatric surgery

Thats a completely different mechanism from how prescription GLP-1 medications like semaglutide (Ozempic, Wegovy) or tirzepatide (Zepbound, Mounjaro) work

doi:10.3390/ijms19010026 81

Novo Nordisk's challenge is that it is now in catch-up mode on efficacy
