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What the Clinical Trial Evidence Shows Phase 2 retatrutide trial data reported gastrointestinal effects as the most common adverse events

Hepatic and Metabolic Benefits A MAFLD/MASLD (metabolic dysfunction-associated steatotic liver disease) sub-study of the Phase 2 obesity trial reported that over 85% of participants on the highest retatrutide doses achieved more than 30% reduction in liver fat content measured by MRI, with many reaching complete resolution of steatosis

Staying hydrated, eating regularly, and resting can help, but ongoing or severe dizziness should be discussed with a clinician

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Here is a detailed breakdown of what evidence-based protocols look like