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Some compounded formulations match or approach this stability, while others may degrade somewhat faster due to different excipients or preservative concentrations
The FDA has pointed to real problems with compounded GLP-1s: dosing errors from patients measuring their own doses out of multi-dose vials (some serious enough to require hospital care), counterfeit or mislabeled products sold online, and products that arrived warm or were stored incorrectly
Patients frequently report diminished hunger within 12 to 36 hours of injection, sometimes before they feel any stomach upset
Among people with type 2 diabetes, tirzepatide led to an average weight loss of 12.814.7% on the two highest doses of Mounjaro
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