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Bupropion in Contrave affects neurotransmitters (dopamine and norepinephrine) that regulate appetite and reward processing, while naltrexone originally used to treat alcohol and opioid dependence blocks opioid receptors in the brains reward system, helping to reduce food cravings

This translates to stable blood sugar and fewer cravingscritical advantages during menopause when blood sugar swings amplify mood changes and hot flash severity

Realistic Expectations Healthy weight loss: 0.51 kg per week Rapid weight loss is not always sustainable Plateaus are normal after initial progress These medications are designed for long-term management , not quick fixes