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Description
patients ages 21 and 70obtained from the TriNetX dataset, which includes 114 million de-identified health records from 80 healthcare organizationswho underwent upper and lower endoscopies between January 1, 2018, and December 21, 2020
GLP-1 receptor agonists work by mimicking the action of endogenous GLP-1, a hormone that stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and promotes satiety through central nervous system pathways
SCFAs may stimulate the release of GLP-1 by binding to the L-cell receptors
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Thus, these neurons are able to sense and respond to a variety of peripheral signals that help to regulate both short and long-term energy balance
