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it has been the manufacturing of the complex, single-use glass auto-injector pens

Ex vivo duodenal segments from Fabp5 / mice secrete significantly less GIP in response to oleic acid with 4 v/v% bile in media than tissues isolated from wild-type mice (Shibue et al., 2015)

It is also, per recent mechanistic work, responsible for PCSK9 degradation, which is the likely pathway behind the LDL cholesterol reductions seen in TRIUMPH-4

Novo Nordisk acquired the Catalant facility in late 2024