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Accompanied by neurologic symptoms such as leg weakness, numbness, bowel or bladder dysfunction, or saddle anesthesiathese are red flags for cauda equina syndrome or severe nerve compression requiring emergency evaluation

The size of each point is a function of the momentum of the study, which is calculated based on the cited by count and weighted by recency

Makers of these drugs recommend having a conversation about the side effect profile and personalized risks with a health care professional before starting

Still, insurance coverage and cost considerations mean both drugs remain relevant, and patient-centred conversations about therapy choice are critical. GLP-1s beyond weight loss as multi-system therapies Liver disease and metabolic steatohepatitis Non-alcoholic fatty liver disease (NAFLD) and the more severe metabolic dysfunction-associated steatohepatitis (MASH) have few effective pharmacologic treatments

Available online: [PubMed] [Google Scholar] 2.Cesta C.E., Rotem R., Bateman B.T., Chodick G., Cohen J.M., Furu K., Gissler M., Huybrechts K.F., Kjerpeseth L.J., Leinonen M.K., et al