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Notably, retatrutide trials showed an overwhelming clearance of liver fat, with some cohorts experiencing up to an 80% reduction in hepatic lipid content, presenting a massive benefit for individuals dealing with metabolic dysfunction-associated steatotic liver disease (MASLD)

Model + CR, obese mice group administrated with calorie restriction(CR group was fed with 70% calories of the Model group per day) [15, 16]

N Engl J Med 383 (11): 1040-1049, 2020

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A broad scan of review articles on nasal sprays shows an emphasis on spray characteristics and the impact on either the deposition patterns in the respiratory tract, the bioavailability, or therapeutic effects (A PubMed search as of 24th Aug 2024 with keywords nasal delivery user experience resulted in 2 results whereas nasal delivery clinical resulted in 2445)