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This imbalance is understandable, as GLP-1 RAs were originally developed for diabetes and weight management, and their effects on substance use have been discovered more recently

All-cause mortality

A 2024 study from Beth Israel Deaconess Medical Center found that about 15 million Americans use the new generation of weight-loss drugs, known as GLP-1 agonists, which require a once-weekly injection

Zone-2 cardio and resistance training are particularly beneficial
