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Finally, we compare the beneficial effects of GLP-1 receptor agonists and meal-induced gut GLP-1 secretion on overeating-induced obesity and discuss how combining these approaches may complement each others limitations and serve as a promising long-term strategy for preventing and treating obesity
Li, X., Jia, F., Zhu, Z

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Despite the absence of a formal interaction, both medications can affect appetite, cardiovascular parameters, and gastrointestinal function in ways that may overlap or compound