small molecule glp-1 agonist A novel approach to exploit Small-Molecule glucagon-like Peptide-1 receptor agonists with high potency PDB-101: Molecule of the Month:
Description
So far about 10 players are expected in the first wave, including Dr Reddy's, Sun Pharma, Lupin, Mankind, Zydus, Cipla, Hetero and Alkem

Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone released from the K-cells of the small intestines and acts on the pancreas to potentiate GSIS (Miyawaki et al., 1999)

Currently, the FDA is advising against the use of GLP1 agonists in people at risk for MTC or MEN2 syndrome ( N Engl J Med

Lancet Diabetes Endocrinol 2016;4:1004-16.ArticlePubMed 121

These medications do not directly target cellular energy production or mitochondrial function
