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[19] [20] Blood pressure effects may contribute to overall cardiorenal risk management in these patients, though standard nephroprotective therapies should be maintained according to current guidelines

Muscle pain (myalgia) is not listed as a common adverse effect in the FDA-approved prescribing information for most GLP-1 receptor agonists

However, the EMPA-REG OUTCOME trial showed Jardiance provides a 38% relative risk reduction in cardiovascular death for patients with established heart disease

Drivers of Recent Interest in GLP-1RA Though GLP-1RAs have been available for close to 20 years, there has been a surge in recent interest amongst the business community

With the looming patent expiry, Roche remains focused on its pipeline and recently announced very promising results for its new breast cancer treatment, inavolisib