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At the N-terminus, the Tyr1 of Tirzepatide makes Van der Waals contact with the receptor residues, the Glu3 forms an ionic bond with Arg183 and a network of hydrogen bonds with Tyr145 and Ser381 of the receptor

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Stop using Mounjaro and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting

In MASLD patients, IL-6 levels are typically elevated, which is associated with increased IL-6 production in the liver compared to healthy individuals [96]