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Individuals with a history of medullary thyroid carcinoma (a rare neuroendocrine tumor known as MTC) or multiple endocrine neoplasia syndrome type 2 (a hereditary cancer known as MEN 2) should not take semaglutide due to an increased risk of thyroid C-cell tumors in rodents

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Harmer D, Falank C, Reagan MR (2019) Interleukin-6 interweaves the bone marrow microenvironment, bone loss, and multiple myeloma