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What social determinants of health, if any, might impact this patients ability to initiate and sustain therapy

Efficacy and safety of the glucagon-like peptide-1 receptor agonist liraglutide added to insulin therapy in poorly regulated patients with type 1 diabetes-a protocol for a randomised, double-blind, placebo-controlled study: the Lira-1 study

[DOI] [PMC free article] [PubMed] [Google Scholar] Gabery S., Salinas C.G., Paulsen S.J., Ahnfelt-Rnne J., Alanentalo T., Baquero A.F., Buckley S.T., Farkas E., Fekete C., Frederiksen K.S., Helms H.C.C., Jeppesen J.F., John L.M., Pyke C., Nhr J., Lu T.T., Polex-Wolf J., Prevot V., Raun K., Simonsen L., Sun G., Szilvsy-Szab A., Willenbrock H., Secher A., Knudsen L.B

Last reviewed: June 18, 2026 Last updated: June 18, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Clinical assessments were conducted every 3 months to evaluate efficacy, measured as percentage of total weight loss (%TWL), excess weight loss (%EWL), changes in BMI, and improvement in comorbidities, as well as tolerance, monitored for adverse effects including gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea) and discontinuation rates