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Atypical femur fractures can present as insidious-onset pain in the subtrochanteric region before any fracture has occurred on imaging

The weight loss and insulin sensitivity improvements associated with orforglipron would be expected to significantly reduce the risk of progression from prediabetes to overt type 2 diabetes

Toujeo and alcohol Alcohol can have different effects on insulin, including insulin glargine, the active ingredient in Toujeo

Lab work schedule Before starting the combination, get baseline labs: comprehensive metabolic panel, lipid panel, fasting insulin, HbA1c, thyroid panel, vitamin D, B12, and a complete blood count

Funding R.J.J