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Berberine may interact with diabetes medications, particularly increasing hypoglycaemia risk when combined with insulin or sulfonylureas, and may affect the metabolism of other medicines through enzyme inhibition

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The idea that one can accurately identify delayed gastric emptying without performing imaging (such as bedside gastric ultrasound) is not rooted in reality

Translating the pharmacology of dual GLP-1/GIP agonists into actionable preclinical data requires tools capable of detecting receptor engagement with cellular and spatial resolution , challenging because GLP-1R and GIPR are low-abundance membrane proteins, and no reliable commercial antibody exists for GIPR detection in primary tissues
