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This combination results in: Lower post-meal glucose spikes Improved insulin sensitivity Reduced appetite and caloric intake These effects make Tirzepatide more effective than traditional GLP-1 receptor agonists (like liraglutide and semaglutide), which only target one pathway

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Exenatide once weekly versus liraglutide once daily in patients with type 2 diabetes (DURATION-6): a randomized, open-label study