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Inflammation, roles in diabetic complications Chronic hyperglycemia, characterized by high blood sugar levels, is strongly associated with increased incidence of inflammatory reactions [24], [25], [26]

doi: 10.1056/NEJMoa0806359 5 ZinmanBWannerCLachinJMFitchettDBluhmkiEHantelSet al

These results suggest that amycretin prevents the downregulation of energy expenditure (often referred to as metabolic adaptation), which can be defined as a lower measured energy expenditure than predicted, occurring in both humans and rodents

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