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Type 2 diabetes mellitus (T2DM) is a widespread metabolic disorder characterized by insulin resistance and pancreatic -cell dysfunction, posing a substantial global health challenge
GLP-1 medications can contribute to fatigue in some patients, though the mechanism varies by individual metabolic state, caloric intake, and genetic factors

This review examines the effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on different heart failure phenotypes with preserved ejection fraction

Truveta Research tracks GLP-1 RA prescribing through March 2026, showing accelerated anti-obesity use and a sharp rise in first-time semaglutide prescribing.
