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Growing evidence shows that insulin resistance (IR) in the brain can challenge neural function, which is why AD is often termed Type 3 diabetes. Current drugs like TRZ, which activates both glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP) receptors, are under investigation for their neuroprotective potential

Adding 2.5 mL of bacteriostatic water to a 5mg vial gives a concentration of 2 mg/mL

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Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $32.99 / 30 days cancel any time Subscribe to this journal Receive 52 print issues and online access $199.00 per year only $3.83 per issue Rent or buy this article Prices vary by article type from$1.95 to$39.95 Prices may be subject to local taxes which are calculated during checkout Nature 608 , 258-260 (2022) doi: References Davis, H

Maintain strict dietary adherence during this time