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Do not use loperamide if there is blood in the stool, high fever, or for more than 48 hours without medical advice

Individual response timelines vary

doi: 10.1016/S0140-6736(20)32205-4 [DOI] [PMC free article] [PubMed] [Google Scholar] 5

Abstract Background: Intestinal dysmotility in type 2 diabetes mellitus (T2DM) may involve impaired cholinergic and incretin-mediated regulation
