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However, this perspective overlooks the broader impact of these medications on optimizing surgical outcomes, reducing complications, and expanding access to surgery for higher-risk patients
Their large peptide structure (Figure 1) makes them prone to enzymatic degradation, lowering bioavailability, and can trigger immunogenicity causing anti-drug antibodies (ADAs)
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3B indicated that, although the P -value exceeded 0.1 and the I 2 statistic was greater than 50%, the presence of heterogeneity could not be disregarded [22, 23]
